Emergent Phenomena in Biology
Our Cell research theme, focuses on unlocking the complexities of life’s fundamental unit: the cell. Living cells are dynamic active materials, where their mechanical properties emerge from a network of filaments and motor molecules. Key processes like cell signaling, volume regulation, and division arise from nanoscale interactions.
To investigate the multi-scale dynamics driving cellular behavior, we are pioneering advanced quantum imaging and sensing technologies. These innovations promise rapid measurement speeds, nanoscale spatial resolution, and ultra-high sensitivity, enabling us to study cells while minimizing damage to delicate biological samples.
Quantum sensing techniques offer exceptional sensitivity, allowing for low-power measurements that reduce the risk of photodamage. By leveraging entangled photon pairs, we can capture fast dynamic processes, facilitating the exploration of molecular interactions within cells. Our aim is to integrate these capabilities with super-resolution microscopy, enhancing imaging techniques for deep tissue studies.
In addition, our research will utilize quantum microscopy to improve measurement precision and spatial resolution across a range of applications, all while protecting biological samples.
These quantum advancements will complement our established classical measurement techniques, such as Raman and Brillouin microscopies, as well as optical tweezers and local viscosity measurements. This multifaceted approach will enable us to investigate complex cellular phenomena, including liquid-liquid phase separation in biomolecular condensates, cell division, and dynamic processes across cellular membranes. Through this work, we aspire to gain deeper insights into the mechanisms that underpin cellular function and life itself.
Contact us
If you would like to work or study with us within this research theme, please contact Cell Theme Lead, A/Professor Irina Kabakova.