What if we could see the invisible? For example, the tiny molecules that signal disease or contamination without harming the cells we’re measuring.

Centre researchers from The University of Queensland have developed a new quantum-enhanced approach to Raman microscopy that uses quantum light to fingerprint molecules in biological samples in greater detail with less damage. This breakthrough could transform how we detect disease, monitor food safety, and study living cells in real time.

The microscope uses a special form of light called squeezed light that allows scientists to gather more information while avoiding damage and disruption on delicate samples. This is a turning point for studying living cells, where traditional imaging methods can be too harsh or too slow to capture fast-moving processes.

The technology builds on QUBIC’s mission to develop quantum tools that reveal how life works at the smallest scales. It’s part of a broader effort to understand how cells function, adapt, and sometimes fail, all insights that are essential for tackling diseases and improving health.

By combining quantum technologies with microscopy, the team has opened a new window into the living world. This technical achievement is an exciting new way to explore life, protect health, and respond to challenges we can’t yet see.

Published paper: Fast biological imaging with quantum-enhanced Raman microscopy (2024)

This impact story is an extract from QUBIC’s 2024 Annual Report: read more.